What is mcv4 vaccine?

MCV4 stands for Meningococcal Conjugate Vaccine, Quadrivalent. It is a vaccine used to provide protection against four serogroups of the bacteria Neisseria meningitidis, which causes meningococcal disease.

There are 13 known serogroups of this bacteria, but serogroups A, B, C, W, and Y cause the majority of meningococcal disease cases. MCV4 specifically targets serogroups A, C, W, and Y.

Here are some key points about MCV4 vaccine:

  1. Types: There are two types of MCV4 vaccines available: conjugate vaccines and polysaccharide vaccines. MCV4 vaccines include both conjugate and polysaccharide vaccines, while there are also standalone conjugate vaccines available, such as MenACWY-D, MenACWY-CRM, and MenACYW-135.

  2. Administration: MCV4 is given as an injection, usually into the muscle of the upper arm or thigh.

  3. Age groups: MCV4 vaccines are recommended for individuals between the ages of 2 months and 55 years. The vaccines are typically administered to adolescents around the ages of 11-12, with a booster dose at 16 years of age. Additionally, certain individuals may require MCV4 vaccination due to travel, college entry requirements, or increased risk of exposure to the bacteria.

  4. Efficacy and coverage: MCV4 provides protection against meningococcal disease caused by serogroups A, C, W, and Y. The vaccine is highly effective in preventing diseases caused by these serogroups.

  5. Side effects: The most common side effects of MCV4 vaccines include pain, redness, and swelling at the injection site. Fatigue, headache, and muscle pain may also occur. Serious side effects are rare.

  6. Contraindications: Individuals who have had a severe allergic reaction to a previous dose of MCV4 or any of its components should not receive the vaccine. People with certain medical conditions should consult with their healthcare provider before getting vaccinated.

It is important to note that MCV4 vaccines do not provide protection against meningococcal serogroup B. A separate vaccine called MenB vaccine is available to protect against meningococcal serogroup B.